White Sox at Tigers Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 4

Friday, April 4 the Chicago White Sox (2-4) are scheduled to be in Motown to take on the Tigers (2-4) in Game 1 of their weekend series.

Jonathan Cannon is slated to take the mound for Chicago against Jack Flaherty for Detroit

The White Sox lost two of three earlier this week to the Minnesota Twins. Harrison Bader and Byron Buxton smacked home runs off Chicago hurlers as the Twin rolled the Pale Sox 6-1 in their series finale.

Detroit lost Wednesday to the Mariners but did take two of the three games in that series. Tarik Skubal is off to an 0-2 start and holds a 5.91 ERA through two starts for the Tigers.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch White Sox at Tigers

  • Date: Friday, April 4, 2025
  • Time: 1:10PM EST
  • Site: Comerica Park
  • City: Detroit, MI
  • Network/Streaming: Chicago Sports Net, FDS

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the White Sox at the Tigers

The latest odds as of Thursday:

  • Moneyline: White Sox (+200), Tigers (-250)
  • Spread:  Tigers -1.5 (-110)
  • Total: 7 runs

Probable starting pitchers for White Sox at Tigers

  • Pitching matchup for April 4, 2025: Jonathan Cannon vs. Jack Flaherty
    • White Sox: Jonathan Cannon (0-0, 0.00 ERA)
      Last outing: 3/29 vs. Angels - 5 IP, 0ER, 4H, 3BB, 5Ks
    • Tigers: Jack Flaherty, (0-0, 3.18 ERA)
      Last outing: 3/28 at Dodgers - 5.2 IP, 2ER, 3H, 2BB, 5Ks

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of White Sox at Tigers

  • The White Sox are 4-2 on the Run Line this season
  • The Tigers are 3-3 on the Run Line this season
  • The White Sox are the only team in the AL Central with a positive run differential (+4) at this point in the season

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & ...

Save Story