Striker Kyle Hudlin will return after two months out when Newport County host Colchester United on Saturday – but defender Cameron Evans looks set to miss the rest of the season.
On-loan Huddersfield player Hudlin, 24, has not played since 11 February because of a calf problem but is expected to play some part at Rodney Parade this weekend.
Fellow frontman Courtney Baker-Richardson is also available after sitting out last weekend's defeat at Carlisle United, but Evans has been told to expect three weeks out after a scan on a hamstring problem.
Former Swansea City youngster Evans, 24, has made 34 appearances in 2024-25.
"It's a big blow for us in terms of what he's been offering to us - he's been a great player throughout this season," said Newport boss Nelson Jardim.
"On the positive side we've got Baker-Richardson back, he managed to go through the fatigue level and he's in a good place.
"Kyle Hudlin is back as well, we've had three, four sessions with him. He's not ready for the full 90 minutes, but he'll be there with us."
Newport are without a victory in four matches and have managed just one win in their past seven games.
They will look to respond to the dispiriting 3-2 defeat at bottom club Carlisle – a game in which Jardim's team led 2-0 - when they take on a Colchester side who are in play-off contention.
The Exiles are 18th in the table, 11 points clear of the relegation places with five games remaining this season.
Jardim rejected the suggestion that his team are already winding down towards the end of the season.
"I disagree with that," the Portuguese said.
"You should see them training, they're pushing. It's just sometimes it's the way we are, we have to change as players."
