Ruben Amorim has already beaten Manchester City twice this season - once with Sporting, and then with Manchester United - but can he make it three wins out of three at OId Trafford on Sunday?
"United don't score enough goals," said BBC Sport football expert Chris Sutton. "That's their biggest problem, although I am still not sure City will keep them out."
Sutton is making predictions for all 380 Premier League games this season, against a variety of guests.
For week 31, he takes on singer-songwriter Mychelle, who supports Chelsea.
Mychelle's latest track, You Don't Care About Me, is out now and she is joining Jorja Smith on the UK leg of her tour, in May and June.
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Mychelle was born and grew up in Stoke Newington, north London, but says there was no chance of her supporting her local club, Arsenal.
"I support Chelsea because of my step-dad - he always had their games on the TV - but my mum is a Tottenham fan and she was adamant that I could not support Arsenal," she told BBC Sport.
"There were not many other Chelsea fans around my estate but funnily enough one of my neighbours was a fan too.
"She was also the only other girl I knew who liked playing football too, so it was a bit of a coincidence that the one person I bonded with at school over football supported the same team I did.
"My hero was Didier Drogba. He was a great player, but he had amazing charisma too. He was so exciting to watch."
As well her musical career, Mychelle still plays football now - as a left-winger for Islington Borough Ladies in the Greater London Women's Football League.
"I didn't play for a while when I left school but then I got spotted playing in Finsbury Park, and invited to play for Islington Borough's beginner group," she explained.
"I loved it, and haven't stopped since - I played seven-a-side at first then 11-a-side for the reserves before I got into the first team.
"It's been an amazing journey and I've made some great friends - I'd recommend it to anyone. It is hard to play every weekend because I might have a gig somewhere, but I always travel back when I can.
"Once, I was playing up in Manchester on the Saturday night but I got the overnight coach back to London afterwards, so I could make Sunday's game. I got home at 7am, had a nap, played the game and then had to go straight to play another gig that evening. It was a bit tiring, but it was worth it!"
Chris Sutton and Mychelle were speaking to BBC Sport's Chris Bevan.
Premier League predictions
Saturday, 5 April
This is going to be difficult for Arsenal. Everton defended so well against Liverpool on Wednesday, and they carried a real threat too, with Beto running in behind.
Bukayo Saka was back for the Gunners against Fulham and he will obviously boost their attack but they have picked up a few defensive injuries, including Gabriel being out for the rest of ...
