Ole Miss vs. Iowa State Prediction: Odds, Expert Picks, Betting Trends, and Stats for 2025 March Madness
The Rebels of Ole Miss (23-11) are set to face the Iowa State Cyclones (25-9) in the second round of the 2025 NCAA Tournament Sunday, in Milwaukee, WI.
In the First Round, Ole Miss held off a late comeback from North Carolina and won 71-64. Senior point guard Sean Pedulla led the team with 20 points, while Dre Davis added 15, including a crucial three-pointer late in the game.
To say Iowa State dominated Lipscomb in Round 1 would not give the Cyclones enough credit. The final score, 82-55, is unfair to Iowa State. Milan Momcilovic led the team with 20 points, and the Cyclones' defense was outstanding. Their physical style set the tone early and was effective throughout the game.
This is also a fascinating matchup of head coaches. Both Chris Beard of Ole Miss and T.J. Otzelberger have experience in the Tournament and excel at game planning as well as adjusting in-game. Will be a fun chess match to watch.
The winner of this game is in the Sweet 16 and will next face the winner of the New Mexico vs. Michigan State game.
Lets dive in a little deeper, offer a little information, and possibly find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch the opening tip, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
Game details & how to watch Ole Miss vs. Iowa State
- Date: Sunday, March 23, 2025
- Time: 7:45PM EST
- Site: Fiserv Forum
- City: Milwaukee, WI
- Network/Streaming: truTV
Never miss a second of the action and stay up to date with all the latest scores and player news. Check out our day-by-dayNCAA Basketball Schedule Page that includes live game updates.
Game odds for Ole Miss vs. Iowa State
The latest odds as of Friday courtesy of BetMGM:
- Odds: Ole Miss Rebels (+190), Iowa State Cyclones (-225)
- Spread: Cyclones -5.5
- Total: 145.5 points
Expert picks & predictions for Ole Miss vs. Iowa State
NBC Sports Bet Best Bet
Our model calculates projections around each moneyline, spread and over/under bet for every game on the NCAA calendar based on data points like past performance, player matchups, injuries, and the schedule.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for Sunday's Rebels & Cyclones game:
- Moneyline: NBC Sports Bet is recommending a play on Iowa State on the Moneyline.
- Spread: NBC Sports Bet is leaning towards a play ATS on Iowa State -5.5.
- Total: NBC Sports Bet is recommending a play on the Game Total UNDER 145.5.
Ole Miss vs. Iowa State: Top betting trends and recent stats
- Ole Miss covered the spread as an underdog in each of their last 2 games (1 win and 1 loss)
- Iowa State was favored by 14 and won by 27 in Round 1 against Lipscomb
- Iowa State has won and covered 3 of their last 4 games
- These teams last met in January of 2019 with Iowa State winning, 87-73, and covering as a 1.5-point favorite
If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out ourNCAA Basketball Top Trends Toolon NBCSports.com!
Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.
Follow our experts on socials to keep up with all the latest content from the staff:
· Jay Croucher (@croucherJD)
· Drew Dinsick (@whale_capper)
· Vaughn Dalzell (@VmoneySports)
· Brad Thomas (@MrBradThomas)
Topics
-
North Carolina vs Ole Miss Prediction: Odds, Expert Picks, Betting Trends and Stats for 2025 March Madness
North Carolina Tar Heels vs. Ole Miss Rebels Game PreviewYahoo Sports - 2d -
Lipscomb vs Iowa State Prediction: Odds, Expert Picks, Betting Trends and Stats for 2025 March Madness
Lipscomb Bison vs. Iowa State Cyclones Game PreviewYahoo Sports - 2d -
Ole Miss basketball vs Iowa State prediction: Our pick for 2025 NCAA tournament second round
It’s the Ole Miss Rebels vs Iowa State in the March Madness bracket. Here’s our prediction for the 2025 NCAA tournament basketball game.Yahoo Sports - 1d -
SEC Tournament - Ole Miss vs. Auburn Predictions: Odds, Expert Picks, Betting Tends, and Recent Stats
Ole Miss Rebels vs. Auburn Tigers Game PreviewYahoo Sports - Mar. 14 -
What channel is Ole Miss basketball vs Iowa State on today? Time, TV schedule to watch March Madness game
What channel is the Ole Miss basketball vs North Carolina March Madness game on today? Here's how to watch, including time, TV schedule, live streaming info and game odds.Yahoo Sports - 48m -
2025 March Madness predictions: NCAA bracket expert picks against the spread, odds in Sunday's Round 2 games
Best bets for Duke-Baylor, Kentucky-Illinois, Iowa State-Ole Miss and more from Sunday's scheduleCBS Sports - 10h -
Utah State vs UCLA Prediction: Odds, Expert Picks, Betting Trends and Stats for 2025 March Madness
Utah State Aggies vs. UCLA Bruins Game PreviewYahoo Sports - 3d -
Alabama State vs Auburn Prediction: Odds, Expert Picks, Betting Trends and Stats for 2025 March Madness
Alabama State Hornets vs. Auburn Tigers Game PreviewYahoo Sports - 3d -
Baylor vs Mississippi State Prediction: Odds, Expert Picks, Betting Trends and Stats for 2025 March Madness
Baylor Bears vs. Mississippi State Bulldogs Game PreviewYahoo Sports - 2d
More from Yahoo Sports
-
Who is the Commanders' best trade asset ahead of the NFL draft?
The Washington Commanders need more picks in the 2025 NFL draft. PFF names their biggest trade asset.Yahoo Sports - 23m -
Who is the Commanders' best trade asset ahead of the NFL draft?
The Washington Commanders need more picks in the 2025 NFL draft. PFF names their biggest trade asset.Yahoo Sports - 23m -
Calipari bests Pitino in March Madness and leads Arkansas to sweetest Sweet 16 appearance yet
John Calipari is heading back to the Sweet 16 after sending a second straight Hall of Famer home from the NCAA Tournament’s “Region of Coaches.” One game after knocking out good friend Bill Self ...Yahoo Sports - 11h -
Giants outfielder Jerar Encarnación to miss start of season with broken left hand
Encarnación hit .302 with two homers and 14 RBIs in spring training.Yahoo Sports - 12h -
Brignone, Odermatt win season-long downhill titles after wind cancels races at World Cup finals
Italian ski racer Federica Brignone and Marco Odermatt of Switzerland earned season-long downhill titles Saturday after the races at World Cup finals were canceled due to high wind. Neither race ...Yahoo Sports - 14h
More in Sports
-
Scaloni on Argentina win: No Messi? No problem
Argentina coach Lionel Scaloni said Friday's win over Uruguay showed their depth after Lautaro Martínez, Lionel Messi and Paulo Dybala all missed out.ESPN - 33m -
Poch: USMNT faces test of 'character' vs. Canada
USMNT coach Mauricio Pochettino said that Sunday's third-place game in the Concacaf Nations League against Canada is a match where "we need to show character."ESPN - 34m -
Wrexham boost promotion hopes with 1-0 win
Wrexham made progress in their hunt for automatic promotion from League One on Saturday as they moved into second place with a 1-0 win over 10-man Stockport County.ESPN - 34m -
Ex-France star Ribery: Leg was nearly amputated
Former Bayern Munich and France winger Franck Ribery has revealed that he almost had his leg amputated towards the end of his career after surgery on his knee.ESPN - 34m -
Ronaldo: 'No problem' with Højlund's 'Siu' celeb
Cristiano Ronaldo said he has "no problem" with Rasmus Højlund performing his famed "Siu" celebration after scoring in Denmark's win over Portugal on Thursday.ESPN - 34m