Ospreys have been left to count the cost of the end of their European adventure after an agonising Challenge Cup quarter-final defeat 20-18 defeat against Lyon.
Influential forward trio Justin Tipuric, Adam Beard and Rhys Davies all picked up injuries and are set to miss the Judgement Day game with Cardiff at the Principality Stadium next Saturday.
"They're being assessed and it is a bit of a mixture," said Ospreys head coach Mark Jones.
"They're obviously not great or they wouldn't have come off if they were.
"They'll probably miss next week based on what we've seen earlier.
"But we've not seen any further than that, so I can't say any further than that without speaking to the physios or the doctor."
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Tipuric concern
Tipuric was forced off early on with a pectoral muscle problem that will make him a doubt for the home game against Dragons on 26 April.
That occasion is being billed as the flanker's last match in Swansea before he retires from playing at the end of the season to become the Ospreys' defence coach.
"He felt something in his pec area that he was uncomfortable with," said Jones.
"When you're a guy in a line-out like he is aerially or uses your hands in the contact area like he does, you've got to be able to use two hands on the rugby field.
"He's a tough cookie so for him to come off, there must have been a serious amount of discomfort for him."
Ospreys are aiming to finish in the top eight of the United Rugby Championship (URC) again and need to beat Matt Sherratt's men to keep that dream alive.
Following two Welsh derbies, Ospreys finish the regular season with two games in South Africa.
"Judgement Day becomes a big focus for us and we hopefully have an opportunity to have a good crack at that," said Jones.
"If we can get some momentum through the next couple of week hopefully we can push for potentially getting in the top eight when we get to South Africa."