Astros at Mariners Prediction: Odds, expert picks, starting pitchers, betting trends and stats for April 7

Its Monday, April 7 and the Astros (4-5) are in Seattle to take on the Mariners (3-7) in a Western Division showdown.

Hayden Wesneski is slated to take the mound for Houston against Logan Gilbert for Seattle

Houston took two of three over the weekend from the Twins. Yesterday, the Astros won, 9-7, in 10 innings. Yordan Alvarez got the bat going for the first time this season going 2-4 with a home run and three RBIs to pace the attack.

Seattle got swept this past weekend by the Giants. They lost yesterday, 5-4, as Mike Yastremski smacked a three-run homer and Wilmer Flores ended the game driving in his twelfth run of the season with a single off od Gregory Santos.

Lets dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch tipoff, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

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Game details & how to watch Astros at Mariners

  • Date: Monday, April 7, 2025
  • Time: 9:40PM EST
  • Site: T-Mobile Park
  • City: Seattle, WA
  • Network/Streaming: SCHN, Root Sports

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Astros at the Mariners

The latest odds as of Monday:

  • Moneyline: Astros (+138), Mariners (-164)
  • Spread:  Mariners -1.5
  • Total: 7.0 runs

Probable starting pitchers for Astros at Mariners

  • Pitching matchup for April 7, 2025: Hayden Wesneski vs. Logan Gilbert
    • Astros: Hayden Wesneski (0-1, 5.40 ERA)
      Last outing: 4/1 vs. Giants - 5IP, 3ER, 2H, 3BB, 6Ks
    • Mariners: Logan Gilbert (0-1, 3.00 ERA
      Last outing: 4/1 vs. Detroit - 5IP, 3ER, 5H, 1BB, 10Ks

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Top betting trends & insights to know ahead of Astros at Mariners

  • The Under is 5-3-1 in Astros' games this season
  • The Under is 6-3-1 in Mariners' games this season
  • Houston is 3-6 on the Run Line this season
  • Seattle is 4-6 on the Run Line this season

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC ...

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